News | October 1, 2012

Multisorb To Present Benefits Of Modeling Program For Oxygen Sensitive Drugs

Source: Multisorb Technologies

Multisorb Technologies is pleased to announce it will be exhibiting at PACK EXPO International 2012, which is being held October 28-31, 2012 in Chicago, Illinois. Pharmaceutical, medical device, in-vitro diagnostic, and combination drug/device product manufacturers won’t want to miss Multisorb’s in-booth symposium,“Preventing Oxidation of Drug Products in their Packaging” on October 30 at 1:00 pm.

Multisorb will demonstrate how pseudo-empirical, real-time stability modeling is a better predictor for long-term stability than ICH accelerated testing. Oxygen permeability of a bottle increases over time, so 6 months of accelerated testing may not be equivalent to 2 years of real-time- testing.  Multisorb’s SimulOx™ uses a precise mathematical model incorporating properties of the packaging, drug, and sorbent to provide an accurate prediction of drug stability. The program is used to optimize sorbent selection and can assist in bottle material selection. With an optimized high-capacity sorbent, a standard inexpensive HDPE bottle can be used over a more expensive specialty bottle.

Before or after the presentation, be sure to see Multisorb’s Drop-In, Fit-In, and Built-In sorbent solutions that are designed to meet the specialized and often complex needs of the healthcare industry.

Drop-In solutions,StabilOx® Packets and Canisters, StripPax® Packets, and SorbiCap® Canisters, are placed directly into the product’s primary packaging. As system solutions, Multisorb’s Drop-In sorbentsare combined with itscomplementaryAPA-series of dispensers, which are engineered specifically to run its related sorbent with unmatched reliability.   Multisorb’s sorbent systems ensure the integrity of your packaging process by offering seamless integration of sorbent placement in packaging presentations.  

Multisorb will be demonstrating its new APA-9000 SorbiCap®Canister Dispenser and its APA-2000 StripPax® Dispenserwith bottling line interface. The APA-9000, which is also a component of the StabilOx® and Multiform® CSF Canister Systems, can dispense up to 300 canisters per minute.  Alternately running dual hoppers, each with a 4,000 canister capacity, supply a single feed bowl that offer FIFO dispensing control, minimizing exposure and the subsequent loss of sorbent capacity. The APA-2000 is the dispenser component of the StripPax® and StabilOx®Systems and can dispense up to 300 packets per minute. Both systems are compatible with a variety of packaging lines. 

Fit-In sorbents offer an integrated solution as they are mounted within a specific space in a device or drug product packaging.  Multiform CSF® Compressed Sorbentcan be custom shaped to fit into an existing space within the device or packaging. Multiform CSF®Compressed Sorbents offer increased sorbent protection per unit volume than traditional loose-fill packets and canisters.  DesiMax®Self-Adhesive Sorbents, another Fit-In solution, require very little space and are secure within the packaging, making them inconspicuous to the consumer.

For even greater customization, PolySorb® Sorbent Components, a Built-In solution, incorporates sorbent into a thermoplastic structural component of the device, giving the device component multifunctional capabilities. 

Whether Drop-In, Fit-In or Built-In Multisorb has the sorbent solution to solve your drug stability challenges. For more information, visit info@multisorb.com.

About Multisorb Technologies
Multisorb Technologies has been an innovator in active packaging technology for more than 50 years. Founded in 1961 by John S. Cullen to protect products against the damaging effects of moisture, today Multisorb is the world leader in the development and production of active packaging components. For more information, visit  www.multisorb.com.

Source: Multisorb Technologies